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Technical Information   Posters   Papers

Application #:
TI0J21
Type:
Application Note
Categories:
Column Performance
Industrial Chemical
Compounds:
tris (2,2'-bipyridyl) ruthenium (II) chloride hexahydrate
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Tris (2,2'-bipyridyl) ruthenium (II) (Dye for dye sensitized solar cell)

Application #:
TI0I51
Type:
Application Note
Categories:
Industrial Chemical
LC-MS
Compounds:
anthraquinone-1,5-disulfonic acid sodium salt
anthraquinone-1-sulfonic acid sodium salt
anthraquinone-1,8-disulfonic acid sodium salt
Column(s):
Scherzo SM-C18 (150 x 2.0mm)

LC-MS: Organic Redox-Flow Battery negative electrolyte (anthraquinonesulfonic acids)

Application #:
TI0I41
Type:
Application Note
Categories:
Column Performance
Industrial Chemical
Compounds:
1,1'-dimethyl-4,4'-bipyridinium dichloride
1,1'-diethyl-4,4'-bipyridinium dibromide
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Organic Redox-Flow Battery negative electrolyte (Methylviologen dichloride, Ethylviologen dibromide)

Application #:
TI0I40
Type:
Application Note
Categories:
Column Performance
Industrial Chemical
Compounds:
1,1'-dimethyl-4,4'-bipyridinium dichloride
1,1'-diethyl-4,4'-bipyridinium dibromide
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Organic Redox-Flow Battery negative electrolyte (Methylviologen dichloride, Ethylviologen dibromide)

Application #:
TI0H25
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
LC-MS
Compounds:
streptomycin
dihydrostreptomycin
Column(s):
Scherzo SM-C18 (100 x 2.0mm)

LC-MS/MS: Streptomycin, dihydrostreptomycin

Application #:
TI0H06
Type:
Application Note
Categories:
Environmental and Agricultural
LC-MS
Compounds:
glufosinate
glyphosate
3-methylphosphinicopropionic acid (3-MPPA)
N-acetylglufosinate
Column(s):
Scherzo SM-C18 (100 x 2.0mm)

LC-MS/MS: Glufosinate metabolites

Application #:
TI0H05
Type:
Application Note
Categories:
Environmental and Agricultural
LC-MS
Compounds:
glyphosate
Column(s):
Scherzo SM-C18 (100 x 2.0mm)

LC-MS/MS: Glyphosate

Application #:
TI0H04
Type:
Application Note
Categories:
Environmental and Agricultural
LC-MS
Compounds:
glyphosate
N-acetylglyphosate
Column(s):
Scherzo SM-C18 (100 x 2.0mm)

LC-MS/MS: Glyphosate, N-acetylglyphosate

Application #:
TI0H03
Type:
Application Note
Categories:
Environmental and Agricultural
LC-MS
Compounds:
glufosinate
glyphosate
Column(s):
Scherzo SM-C18 (100 x 2.0mm)

LC-MS/MS: Glyphosate, Glufosinate

Application #:
TI0G73
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
LC-MS
Compounds:
neomycin B
neomycin C
Column(s):
Scherzo SM-C18 (250 x 3.0mm)

LC-MS: Neomycin B and C

Application #:
TI0G70
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
LC-MS
Compounds:
spectinomycin
streptomycin
dihydrostreptomycin
neomycin
Column(s):
Scherzo SM-C18 (100 x 3.0mm)

LC-MS: Aminoglycoside antibiotics

Application #:
TI0G23
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
gramine
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Gramine (Indole alkaloid)

Application #:
TI0F93
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
LC-MS
Compounds:
calcium folinate
Column(s):
Scherzo SW-C18 (100 x 3.0mm)
Scherzo SM-C18 (100 x 3.0mm)
Scherzo SS-C18 (100 x 3.0mm)

LC-MS: Folinic acid (Antifolate)

Application #:
TI0F83
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
calcium folinate
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Folinic acid (Antifolate)

Application #:
TI0F61
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
tenofovir
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Tenofovir (Antiviral)

Application #:
TI0E98
Type:
Application Note
Categories:
Column Performance
Industrial Chemical
Compounds:
2-aminophenylboronic acid
3-aminophenylboronic acid
4-aminophenylboronic acid
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Aminophenylboronic acid

Application #:
TI0E69
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
LC-MS
Compounds:
dobesilate
Column(s):
Scherzo SM-C18 (100 x 3.0mm)

LC-MS: Dobesilate (Vasoprotectives)

Application #:
TI0E68
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
dobesilate
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Dobesilate (Vasoprotectives)

Application #:
TI0E58
Type:
Application Note
Categories:
Column Performance
Food Chemistry
Industrial Chemical
Biochemistry/Metabolism
Compounds:
mandelic acid
phenylglyoxylic acid
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Styrene urinary metabolites

Application #:
TI0E51
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Compounds:
adrenaline (epinephrine)
lidocain
Column(s):
Scherzo SM-C18 (100 x 4.6mm)

Adrenaline, lidocain (Local anesthetics)

Application #:
TI0E46
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
adrenaline (epinephrine)
lidocain
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Adrenaline, lidocain (Local anesthetics)

Application #:
TI0E31
Type:
Application Note
Categories:
Column Performance
Industrial Chemical
LC-MS
Compounds:
2,6-diaminotoluene
2,4-diaminotoluene
1,6-hexanediamine
4,4'-diaminodiphenylmethane
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

LC-MS: Isocyanate metabolites

Application #:
TI0E25
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Compounds:
2-Quinolinol (2Q)
3-Quinolinol (3Q)
4-Quinolinol (4Q)
5-Quinolinol (5Q)
6-Quinolinol (6Q)
7-Quinolinol (7Q)
8-Quinolinol (8Q)
Column(s):
Scherzo SM-C18 (150 x 4.6mm)

Quinolinol isomers

Application #:
TI0E00
Type:
Application Note
Categories:
Food Chemistry
LC-MS
Compounds:
nisin
natamycin
Column(s):
Scherzo SM-C18 (100 x 3.0mm)

LC-MS: Nisin, Natamycin (Food preservatives)

Application #:
TI0D88
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
pinaverium
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Pinaverium (Antispasmodic)

Application #:
TI0D83
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
2-chloronicotinic acid
5-chloronicotinic acid
6-chloronicotinic acid
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Chloronicotinic acid isomers

Application #:
TI0D78
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
5-aminosalicylic acid (mesalazine)
3-aminosalicylic acid
4-aminosalicylic acid
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Mesalazine (Anti-inflammatory) and isomers

Application #:
TI0D62
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
ganciclovir
aciclovir
Column(s):
Scherzo SW-C18 (150 x 4.6mm)
Scherzo SM-C18 (150 x 4.6mm)
Scherzo SS-C18 (150 x 4.6mm)

Ganciclovir, Aciclovir (Antiviral)

Application #:
TI0D49
Type:
Application Note
Categories:
Industrial Chemical
LC-MS
Compounds:
N,N'-Bis(2,2,6,6-tetramethylpiperidin-4-yl) hexane-1,6-diamine
N1,N3-Bis(2,2,6,6-tetramethylpiperidin-4-yl) isophthalamide
Bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate
Bis(1,2,2,6,6-pentamethyl-4-piperidyl) sebacate
Bis(2,2,6,6-tetramethyl-4-piperidyl-1-oxyl) sebacate
Bis(1,2,2,6,6-pentamethyl-4-piperidyl) butyl (3,5-ditert-butyl-4-hydroxybenzyl) malonate
Column(s):
Scherzo SM-C18 (100 x 3.0mm)

LC-MS: Hindered amine light stabilizers

Application #:
TI0D39
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
carbazochrome sodium sulfonate
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Carbazochrome (Hemostatic)

Application #:
TI0D38
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
carbazochrome
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Carbazochrome (Hemostatic)

Application #:
TI0D30
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
edoxaban
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Edoxaban (Anticoagulants)

Application #:
TI0D29
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
LC-MS
Compounds:
warfarin
coumatetralyl
diphenadione (diphacinone)
Column(s):
Scherzo SM-C18 (100 x 3.0mm)

LC-MS: Anticoagulants

Application #:
TI0D23
Type:
Application Note
Categories:
Biochemistry/Metabolism
LC-MS
Amino Acids and Peptides
Compounds:
methyl-Ser
methyl-Val
methyl-Thr
methyl-Pro
methyl-Met
methyl-Ala
ethyl-Gly
methyl-Tyr
methyl-(Cys)2
ethyl-Leu
methyl-Leu
methyl-Ile
methyl-His
diethyl-Asp
methyl-Phe
methyl-Lys
diethyl-Glu
methyl-Arg
methyl-Trp
Column(s):
Scherzo SM-C18 (100 x 3.0mm)

LC-MS: C-protected amino acids

Application #:
TI0D22
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
trimetazidine
Column(s):
Scherzo SM-C18 (100 x 4.6mm)

Trimetazidine (Vasodilator)

Application #:
TI0D13
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
diphenadione
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Diphenadione (Indandione Anticoagulant)

Application #:
TI0C75
Type:
Application Note
Categories:
Environmental and Agricultural
LC-MS
Compounds:
simazine
atrazine
simetryn
ametryn
prometryn
terbutryn
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

LC-MS: Triazine herbicides

Application #:
TI0C53
Type:
Application Note
Categories:
Environmental and Agricultural
LC-MS
Compounds:
acephate
Column(s):
Scherzo SW-C18 (100 x 3.0mm)
Scherzo SM-C18 (100 x 3.0mm)
Scherzo SS-C18 (100 x 3.0mm)

LC-MS: Acephate

Application #:
TI0C51
Type:
Application Note
Categories:
LC-MS
Compounds:
psilocin
psilocybin
baeocystin
Column(s):
Scherzo SM-C18 (150 x 2.0mm)

High Resolution Accurate Mass (HRAM) Analysis of "Magic" Mushroom Psychedelics

Application #:
TI0B93
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
fexofenadine
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Fexofenadine (Allergic rhinitis, Opioid receptor agonist)

Application #:
TI0B84
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
picosulfate
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Picosulfate (Laxative)

Application #:
TI0B76
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
tranexamic acid
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Tranexamic acid (Anti-inflammatory)

Application #:
TI0B75
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
glycyrrhizic acid
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Glycyrrhizic acid (Anti-inflammatory)

Application #:
TI0B68
Type:
Application Note
Categories:
Column Performance
Environmental and Agricultural
LC-MS
Compounds:
chlormequat chloride
Column(s):
Scherzo SW-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 3.0mm)
Scherzo SS-C18 (150 x 3.0mm)

LC-MS: Chlormequat (Plant growth retardant)

Application #:
TI0B67
Type:
Application Note
Categories:
Column Performance
Environmental and Agricultural
LC-MS
Compounds:
chlormequat chloride
Column(s):
Scherzo SW-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 3.0mm)
Scherzo SS-C18 (150 x 3.0mm)

LC-MS: Chlormequat (Plant growth retardant)

Application #:
TI0B61
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
amlodipine
benzenesulfonic acid
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Amlodipine besilate (Antidepressant)

Application #:
TI0B14
Type:
Application Note
Categories:
Food Chemistry
LC-MS
Compounds:
gallocatechin GC(+)
catechin C(+)
epigallocatechin gallate EGCg(-)
epigallocatechin EGC(-)
epicatechin EC(-)
gallocatechin gallate GCg(-)
epicatechin gallate ECg(-)
catechin gallate Cg(-)
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

LC-MS: Catechin Mixture from Green Tea

Application #:
TI0B13
Type:
Application Note
Categories:
Food Chemistry
LC-MS
Compounds:
gallocatechin GC(+)
catechin C(+)
epigallocatechin gallate EGCg(-)
epigallocatechin EGC(-)
epicatechin EC(-)
gallocatechin gallate GCg(-)
epicatechin gallate ECg(-)
catechin gallate Cg(-)
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

LC-MS: Catechins in Black Tea with tea bag

Application #:
TI0B07
Type:
Application Note
Categories:
Food Chemistry
LC-MS
Compounds:
gallocatechin GC(+)
catechin C(+)
epigallocatechin gallate EGCg(-)
epigallocatechin EGC(-)
epicatechin EC(-)
gallocatechin gallate GCg(-)
epicatechin gallate ECg(-)
catechin gallate Cg(-)
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

LC-MS: Catechins in Black Tea Beverage

Application #:
TI0A94
Type:
Application Note
Categories:
Column Performance
Biochemistry/Metabolism
Saccharides
LC-MS
Amino Acids and Peptides
Compounds:
fructosevaline (fructosylvaline)
fructoselysine (fructosyllysine)
pentosidine
Column(s):
Scherzo SW-C18 (100 x 3.0mm)
Scherzo SM-C18 (100 x 3.0mm)
Scherzo SS-C18 (100 x 3.0mm)

LC-MS: HbA1c and AGEs related amadori compounds

Application #:
TI0A91
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
metformin
Column(s):
Scherzo SW-C18 (100 x 4.6mm)
Scherzo SM-C18 (100 x 4.6mm)
Scherzo SS-C18 (100 x 4.6mm)

Oral hypoglycemic drug (metformin)

Application #:
TI0A87
Type:
Application Note
Categories:
Column Performance
Biochemistry/Metabolism
LC-MS
Compounds:
1,4-diazabicyclo[2.2.2]octane diazabicyclooctane (DBO)
1,5-diazabicyclo[4.3.0]non-5-ene diazabicyclononene (DBN)
1,8-diazabicyclo[5.4.0]undec-7-ene diazabicycloundecene (DBU)
Column(s):
Scherzo SW-C18 (100 x 3.0mm)
Scherzo SM-C18 (100 x 3.0mm)
Scherzo SS-C18 (100 x 3.0mm)

LC-MS: Strong organic base catalysts

Application #:
TI0A86
Type:
Application Note
Categories:
Column Performance
Industrial Chemical
DNA Related Compounds
Biochemistry/Metabolism
LC-MS
Compounds:
imidazole
2-methylimidazole
1-methylimidazole
4-methylimidazole
Column(s):
Scherzo SW-C18 (100 x 3.0mm)
Scherzo SM-C18 (100 x 3.0mm)
Scherzo SS-C18 (100 x 3.0mm)

LC-MS: Methylmidazole isomers

Application #:
TI0A85
Type:
Application Note
Categories:
Column Performance
LC-MS
Amino Acids and Peptides
Compounds:
O-phosphoserine
O-phosphotyrosine
O-phosphothreonine
Column(s):
Scherzo SM-C18 (100 x 2.0mm)

LC-MS: Phosphorylated amino acids

Application #:
TI0A75
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
LC-MS
Compounds:
mesylic acid (methanesulfonic acid)
nelfinavir
Column(s):
Scherzo SW-C18 (50 x 3.0mm)
Scherzo SM-C18 (50 x 3.0mm)
Scherzo SS-C18 (50 x 3.0mm)

LC-MS: Nelfinavir mesylate (antiretroviral drug)

Application #:
TI0A72
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
LC-MS
Compounds:
maleic acid
chlorpheniramine
Column(s):
Scherzo SW-C18 (100 x 3.0mm)
Scherzo SM-C18 (100 x 3.0mm)
Scherzo SS-C18 (100 x 3.0mm)

LC-MS: Chlorpheniramne maleate (antihistamine)

Application #:
TI0A62
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
rizatriptan
benzoic acid
Column(s):
Scherzo SW-C18 (50 x 3.0mm)
Scherzo SM-C18 (50 x 3.0mm)
Scherzo SS-C18 (50 x 3.0mm)

Rizatriptan benzoate (treatment of migraine headaches)

Application #:
TI0A61
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
vancomycin
Column(s):
Scherzo SW-C18 (50 x 3.0mm)
Scherzo SM-C18 (50 x 3.0mm)
Scherzo SS-C18 (50 x 3.0mm)

Antibiotic (vancomycin)

Application #:
TI0A60
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
tizanidine
Column(s):
Scherzo SW-C18 (50 x 3.0mm)
Scherzo SM-C18 (50 x 3.0mm)
Scherzo SS-C18 (50 x 3.0mm)

Tizanidine (muscle relaxant)

Application #:
TI0A59
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
tadalafil
Column(s):
Scherzo SW-C18 (50 x 3.0mm)
Scherzo SM-C18 (50 x 3.0mm)
Scherzo SS-C18 (50 x 3.0mm)

Tadalafil

Application #:
TI0A58
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
eperisone
Column(s):
Scherzo SW-C18 (50 x 3.0mm)
Scherzo SM-C18 (50 x 3.0mm)
Scherzo SS-C18 (50 x 3.0mm)

Eperisone (antispasmodic)

Application #:
TI0A57
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
etodolac
Column(s):
Scherzo SW-C18 (50 x 3.0mm)
Scherzo SM-C18 (50 x 3.0mm)
Scherzo SS-C18 (50 x 3.0mm)

Etodolac (nonsteroidal anti-inflammatory drug, NSAIDs)

Application #:
TI0A49
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
LC-MS
Compounds:
amezinium methylsulfate
Column(s):
Scherzo SM-C18 (50 x 3.0mm)
Scherzo SS-C18 (50 x 3.0mm)

LC-MS: Amezinium methylsulfate (Antihypotentive drug)

Application #:
TI0A25
Type:
Application Note
Categories:
Column Performance
Pharmaceuticals and Cosmetics
Compounds:
rizatriptan
benzoic acid
Column(s):
Scherzo SM-C18 (50 x 3.0mm)
Cadenza CD-C18 (50 x 3.0mm)

Rizatriptan benzoate (treatment of migraine headaches)

Application #:
TI0A14
Type:
Application Note
Categories:
Environmental and Agricultural
LC-MS
Compounds:
glufosinate
fosetyl
paraquat dichloride
glyphosate
diquat dibromide
Column(s):
Scherzo SM-C18 (100 x 2.0mm)

LC-MS: Organophosphorus and quaternary ammonium pesticides/herbicides

Application #:
TI0987
Type:
Application Note
Categories:
Column Performance
Environmental and Agricultural
LC-MS
Compounds:
glufosinate
glyphosate
fosetyl
Column(s):
Scherzo SM-C18 (100 x 2.0mm)

LC-MS: Organophosphorus pesticides/herbicides

Application #:
TI0985
Type:
Application Note
Categories:
Industrial Chemical
Environmental and Agricultural
Compounds:
benzethonium chloride
benzalkonium chloride
Column(s):
Scherzo SM-C18 (100 x 3.0mm)

Benzethonium chloride, Benzalkonium chloride

Application #:
TI0969
Type:
Application Note
Categories:
LC-MS
Pharmaceuticals and Cosmetics
Compounds:
streptomycin
amikacin
kanamycin
spectinomycin
tobramycin
gentamicin C1
gentamicin C2
gentamicin C2b
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

LC-MS: aminoglycoside antibiotics

Application #:
TI0968
Type:
Application Note
Categories:
LC-MS
Compounds:
spermidine
putrescine
cadaverine
spermine
1,3-propanediamine
norspermidine
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

LC-MS: biogenic polyamines

Application #:
TI0960
Type:
Application Note
Categories:
LC-MS
Industrial Chemical
Compounds:
Fe (III)-EDTA
Cu (II)-EDTA
Column(s):
Scherzo SM-C18 (100 x 2.0mm)

LC-MS: Fe(III)-EDTA and Cu (II)-EDTA

Application #:
TI0959
Type:
Application Note
Categories:
LC-MS
Industrial Chemical
Compounds:
Nitrilotriacetic acid (NTA)
Ethylenediaminetetraacetic acid (EDTA)
Diethylentriaminepentaacetic acid (DTPA)
Column(s):
Scherzo SM-C18 (100 x 2.0mm)

LC-MS: EDTA and Related Compounds

Application #:
TI0957
Type:
Application Note
Categories:
LC-MS
Industrial Chemical
Compounds:
1-butyl-1-methylpyrrolidinium
bis(trifluoromethylsulfonyl)imide
Column(s):
Scherzo SM-C18 (50 x 3.0mm)

LC-MS: Ionic Lquid (1-butyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide)

Application #:
TI0955
Type:
Application Note
Categories:
Column Performance
LC-MS
Biochemistry/Metabolism
Amino Acids and Peptides
Compounds:
Phosphoserine
Column(s):
Scherzo SM-C18 (100 x 2.0mm)

Metal-Free Column: phosphoserine

Application #:
TI0954
Type:
Application Note
Categories:
Column Performance
LC-MS
Compounds:
Picolinic acid
Column(s):
Scherzo SM-C18 (100 x 2.0mm)

Metal Free Column: picolinic acid

Application #:
TI0887
Type:
Application Note
Categories:
Food Chemistry
Compounds:
Na+
Cl-
Column(s):
Scherzo SM-C18 (150 x 2.0mm)

NaCl (sodium chloride) in Ramen Soup

Application #:
TI0886
Type:
Application Note
Categories:
Food Chemistry
Amino Acids and Peptides
Compounds:
S-allyl-L-cystein
Column(s):
Scherzo SM-C18 (150 x 4.6mm)

S-allyl-L-cysteine in Garlic Extract

Application #:
TI0883
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Biochemistry/Metabolism
Compounds:
Histamine
Column(s):
Scherzo SM-C18 (150 x 4.6mm)

Histamine

Application #:
TI0854
Type:
Application Note
Categories:
LC-MS
Biochemistry/Metabolism
Column Performance
Compounds:
triiodothyronine (T3)(L-3,3',5-triiodothyronine)
thyroxine (T4)(L-3,5,3',5'-tetraiodothyronine)
Column(s):
Scherzo SM-C18 (50 x 3.0mm)
Cadenza CW-C18 (50 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)
Unison UK-C8 (50 x 3.0mm)
Unison UK-Phenyl (50 x 3.0mm)

LC-MS: Thyroid hormone

Application #:
TI0853
Type:
Application Note
Categories:
LC-MS
Biochemistry/Metabolism
Compounds:
triiodothyronine (T3) (L-3,3',5-triiodothyronine)
thyroxine (T4) (L-3,5,3',5'-tetraiodothyronine)
Column(s):
Intrada Amino Acid (50 x 3.0mm)
Scherzo SM-C18 (50 x 3.0mm)

LC-MS: Thyroid hormone

Application #:
TI0806
Type:
Application Note
Categories:
LC-MS
Biochemistry/Metabolism
Synthetic Polymers
Compounds:
ethylenediamine
hexamethylenediamine
diethylenetriamine
triethylenetetramine
tetraethylenepentamine
bis(6-aminohexyl)amine
Column(s):
Scherzo SM-C18 (50 x 3.0mm)

LC-MS: Synthetic polyamines

Application #:
TI0805
Type:
Application Note
Categories:
LC-MS
Biochemistry/Metabolism
Compounds:
1,3-propanediamine
putrescine
cadaverine
norspermidine
spermidine
spermine
Column(s):
Scherzo SM-C18 (50 x 3.0mm)

LC-MS: Biogenic polyamines

Application #:
TI0795
Type:
Application Note
Categories:
LC-MS
Biochemistry/Metabolism
Compounds:
adenosine monophosphate (AMP)
adenosine diphosphate (ADP)
adenosine triphosphate (ATP)
Column(s):
Scherzo SM-C18 (10 x 3.0mm)

LC-MS: Adenosine phosphates (AMP,ADP, ATP)

Application #:
TI0785
Type:
Application Note
Categories:
LC-MS
Vitamins
Compounds:
dehydroascorbic acid
L-ascorbic acid
isoascorbic acid
L-ascorbic acid 2-glucoside
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

LC-MS: Ascorbic acid related compounds

Application #:
TI0781
Type:
Application Note
Categories:
Amino Acid and Peptides
LC-MS
Compounds:
L-ornithine
putresine
L-phenylalanine
phenethylamine
L-lysine
cadaverine
L-tryptophan
tryptamine
L-hystidine
histamine
L-tyrosine
tyramine
L-arginine
agmatine
Column(s):
Scherzo SM-C18 (100 x 3.0mm)

LC-MS: biogenic amines and precursor amino acids

Application #:
TI0778
Type:
Application Note
Categories:
Industrial Chemical
LC-MS
Compounds:
bis(4-tert-butylphenyl)iodonium
hexafluorophosphate
diphenyl-2,4,6-trimethylphenylsulfonium
p-toluenesulfonate
Column(s):
Scherzo SM-C18 (100 x 3.0mm)

LC-MS: Photo Acid Generators

Application #:
TI0767
Type:
Application Note
Categories:
Industrial Chemical
Compounds:
NaAsO2
Na2HAsO4-7H2O
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

Oxoacids of arsenic

Application #:
TI0766
Type:
Application Note
Categories:
Food Chemistry
Industrial Chemical
Compounds:
Na+
Cl-
Br-
I-
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Scherzo SS-C18 (150 x 3.0mm)

Sodium Halides

Application #:
TI0757
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
LC-MS
Compounds:
alendronic acid
zoledronic acid
risedronic acid
etidronic acid
Column(s):
Scherzo SM-C18 (100 x 3.0mm)

LC-MS: Bisphosphonates (bone resorption inhibitors)

Application #:
TI0756
Type:
Application Note
Categories:
Industrial Chemical
Compounds:
NaNO3
NaNO2
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

Oxoacids of notrogen

Application #:
TI0755
Type:
Application Note
Categories:
Industrial Chemical
Compounds:
NaClO4
NaClO3
NaClO2
NaClO
Na+
Cl-
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

Oxoacids of chlorine

Application #:
TI0754
Type:
Application Note
Categories:
Industrial Chemical
Compounds:
NaIO4
Na+
I-
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

Oxoacid of iodine

Application #:
TI0753
Type:
Application Note
Categories:
Food Chemistry
Industrial Chemical
Compounds:
Na+
Cl-
Br-
I-
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

Sodium Halides

Application #:
TI0749
Type:
Application Note
Categories:
Vitamins
Clinical Diagnostics
Compounds:
Vitamin B7 (biotin)
Column(s):
Scherzo SM-C18 (150 x 2.0mm)

A high throughput solid phase extraction method for vitamin B7 (biotin) from pooled human serum prior to mixed mode LC-MS/MS

Application #:
TI0732
Type:
Application Note
Categories:
Biochemistry/Metabolism
Vitamins
Industrial Chemical
Food Chemistry
Compounds:
"isoascorbic acid (erythorbic acid)
L-ascorbic acid
L-ascorbic acid 2-glucoside"
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-Amino (75 x 3.0mm)

The Scherzo SM-C18 and Unison UK-Amino columns successfully separate the small, polar ascorbic acid related compounds in normal phase mode.

Application #:
TI0731
Type:
Application Note
Categories:
Biochemistry/Metabolism
Compounds:
shikimic acid
L-tyrosine
L-phenylalanine
L-tryptophan
Column(s):
Scherzo SW-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 3.0mm)
Scherzo SS-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

The Scherzo SS-C18 column provides better retention of Shikimic Acid than a standard C18 column.

Application #:
TI0725
Type:
Application Note
Categories:
Amino Acids and Peptides
Biochemistry/Metabolism
Compounds:
angiotensin II (human)
angiotensin IV (human)
[val5]-angiotensin I (bovine)
angiotensin I (human)
angiotensin III (human)
Column(s):
Scherzo SW-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Oligopeptides (angiotensins)

Application #:
TI0720
Type:
Application Note
Categories:
Biochemistry/Metabolism
Botanicals
Compounds:
Shikimic acid
malic acid
Column(s):
Scherzo SW-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 3.0mm)
Scherzo SS-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

The Scherzo SM-C18 and Scherzo SS-C18 column resolve very polar carboxylic acids that normally co-elute on a standard C18 column (Unison UK-C18).

Application #:
TI0719
Type:
Application Note
Categories:
Biochemistry/Metabolism
Compounds:
Prostaglandin F2
Prostaglandin E2
Column(s):
Scherzo SW-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 3.0mm)
Scherzo SS-C18 (150 x 3.0mm)

The Scherzo SS-C18 column retains Prostaglandins the most, followed by Scherzo SM-C18 and Scherzo SW-C18.

Application #:
TI0714
Type:
Application Note
Categories:
Botanicals
Food Chemistry
Compounds:
inositol hexaphosphate (phytic acid )
Column(s):
Scherzo SM-C18 (50 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)

The Scherzo SM-C18 column is able to retain a highly polar compound (multiple phosphate groups) better than a standard C18 column.

Application #:
TI0710
Type:
Application Note
Categories:
Biochemistry and Metabolism
Compounds:
CTP
UTP
TTP
dCTP
GTP
ATP
dGTP
dTTP
dATP
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

The Scherzo SM-C18 column successfully resolves nucleotide triphosphates of similar structure.

Application #:
TI0704
Type:
Application Note
Categories:
Biochemistry/Metabolism
Compounds:
Spermine and spermidine
Column(s):
Scherzo SM-C18 (75 x 3.0mm)
Unison UK-C18 (75 x 3.0mm)

The Scherzo SM-C18 column can separate these two molecules, which would normally coelute on a standard C18 column.

Application #:
TI0703
Type:
Application Note
Categories:
Industrial Chemical
Compounds:
Formic acid and acetic acid
Column(s):
Scherzo SW-C18 (250 x 3.0mm)
Scherzo SM-C18 (250 x 3.0mm)
Scherzo SS-C18 (250 x 3.0mm)
Unison UK-C18 (250 x 3.0mm)

The Scherzo SM-C18 and SS-C18 show excellent resolution of these small molecules, which normally coelute on a standard C18 column.

Application #:
TI0702
Type:
Application Note
Categories:
Environmental and Agricultural
Compounds:
Arsenobetaine
Column(s):
Scherzo SW-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 3.0mm)
Scherzo SS-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

The Scherzo SS-C18 column shows improved resolution of arsenobetaine compared to a standard C18 column. The Scherzo SM-C18 and the Scherzo SW-C18 show similar retention of this zwitterion as the standard Unison UK-C18 column.

Application #:
TI0701
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Botanicals
Biochemistry/Metabolism
Compounds:
Allantoin
allantoic acid and uric acid
Column(s):
Scherzo SW-C18 (250 x 3.0mm)
Scherzo SM-C18 (250 x 3.0mm)
Scherzo SS-C18 (250 x 3.0mm)
Unison UK-C18 (250 x 3.0mm)

The Scherzo SM-C18 and the Scherzo SW-C18 show similar retention of these small molecules as the standard Unison UK-C18. However, the Scherzo SS-C18 shows the best resolution between these three compounds.

Application #:
TI0700
Type:
Application Note
Categories:
Saccharides
Amino Acids and Peptides
Compounds:
Sialylglycopeptide
Column(s):
Scherzo SW-C18 (250 x 3.0mm)
Scherzo SM-C18 (250 x 3.0mm)
Scherzo SS-C18 (250 x 3.0mm)
Unison UK-C18 (250 x 3.0mm)

The Scherzo family columns can separate this glycopeptide with varying retention. The Scherzo SW-C18 has the least retention, followed by the Scherzo SM-C18, followed by the Scherzo SS-C18 which has the most retention.

Application #:
TI0699
Type:
Application Note
Categories:
Saccharides
Amino Acids and Peptides
Compounds:
Sialylglycopeptide
Column(s):
Scherzo SW-C18 (250 x 3.0mm)
Scherzo SM-C18 (250 x 3.0mm)
Unison UK-C18 (250 x 3.0mm)

The Scherzo SM-C18 and SW-C18 columns can separate this glycopeptide with varying retention. The Scherzo SM-C18 has less retention while the Scherzo SW-C18 has more retention.

Application #:
TI0690
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Compounds:
Ibuprofen
Chlorpheniramine
Column(s):
Scherzo SW-C18 (150 x 4.6mm)
Scherzo SM-C18 (150 x 4.6mm)

Both Scherzo SM-C18 and Scherzo SW-C18 can separate an acidic compound (Ibuprofen) and a basic compound (Chlorpheniramine) at the same time. Scherzo SW-C18 works better under gradient elution, whereas Scherzo SM-C18 works better under isocratic elution.

Application #:
TI0689
Type:
Application Note
Categories:
Botanicals
Pharmaceuticals and Cosmetics
Compounds:
trans-resveratrol
cis-resveratrol
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Cadenza CD-C18 (150 x 3.0mm)
Cadenza CW-C18 (150 x 3.0mm)
Cadenza CL-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)
Presto FF-C18 (150 x 3.0mm)

All of the columns listed can recognize the structural difference between these two isomers, and resolve them into two separate peaks.

Application #:
TI0683
Type:
Application Note
Categories:
Biochemistry/Metabolism
Compounds:
"5-hydroxy-L-tryptophan
serotonin
L-tryptophan
5-hydroxyindole -3-acetic acid (5-HIAA)"
Column(s):
Scherzo SW-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 3.0mm)
Scherzo SS-C18 (150 x 3.0mm)

Serotonin related compounds

Application #:
TI0679
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Compounds:
" acetaminophen
N-acetyl-4-benzoquinone imine"
Column(s):
Scherzo SW-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 3.0mm)
Scherzo SS-C18 (150 x 3.0mm)
Cadenza CL-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Acetaminophen and metabolite

Application #:
TI0678
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Compounds:
" acetaminophen
N-acetyl-4-benzoquinone imine"
Column(s):
Scherzo SW-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 3.0mm)
Scherzo SS-C18 (150 x 3.0mm)
Cadenza CL-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Acetaminophen and metabolite

Application #:
TI0669
Type:
Application Note
Categories:
Biochemistry/Metabolism
Pharmaceuticals and Cosmetics
Compounds:
gamma-aminobutyric acid (GABA)
D,L-noradrenaline ((D,L-norepinephrine)
D,L-adrenaline (D,L-epinephrine)
3,4-dihydroxy-L-phenylalanine (L-DOPA)
dopamine
Column(s):
Scherzo SW-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 3.0mm)
Scherzo SS-C18 (150 x 3.0mm)

Catecholamines

Application #:
TI0667
Type:
Application Note
Categories:
Environmental and Agricultural
Compounds:
beta-endosulfan
alpha-endosulfan
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Cadenza CD-C18 (150 x 3.0mm)
Cadenza CL-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Endosulfan isomers

Application #:
TI0665
Type:
Application Note
Categories:
Industrial Chemical
Compounds:
Cr(III) and Cr(VI)
Column(s):
Scherzo SM-C18 (50 x 3.0mm)

LC-ICP-MS analysis of Cr(III) and Cr(VI)

Application #:
TI0664
Type:
Application Note
Categories:
Industrial Chemical
Environmental and Agricultural
Compounds:
glyphosate
AMPA (metabolite)
glufosinate
MPPA (metabolite)
bialaphos
Column(s):
Scherzo SM-C18 (30 x 3.0mm)

LC-MS analysis of phosphorus-containing amino acid type herbicides and their metabolites

Application #:
TI0662
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Compounds:
penicillin G
methicillin
ampicillin
amoxicillin
carbenicillin
Column(s):
Scherzo SM-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)

Penicillin Antibiotics

Application #:
TI0659
Type:
Application Note
Categories:
Food Chemistry
Compounds:
(E)-beta-farnesene
Column(s):
Scherzo SM-C18 (250 x 4.6mm)
Cadenza CD-C18 (250 x 4.6mm)
Cadenza CL-C18 (250 x 4.6mm)
Unison UK-C18 (250 x 4.6mm)

Farnesene isomers

Application #:
TI0652
Type:
Application Note
Categories:
Column Performance
Biochemistry/Metabolism
LC-MS
Compounds:
alanine
N,N-dimethylglycine
serine
fumaric acid
succinic acid
cysteine
oxaloacetic acid
Gly-Gly
malic acid
alpha-ketoglutarate
citric acid
2-methylhippuric acid
gamma-D-glutamylglycine
salbutomal
AMP
ribo-avin
Phe-gly-phe-gly
s-(p-nitrobenzyl) glutathione
s-(p-azidophenacyl)glutathione
taurocholic acid
O-beta-D-glucuronosyl-naphthol AS-BI
Leucine enkephalin
Arg-Pro-Pro-Gly-Phe
Reserpine
GSSG
Arg-Lys-Asp-Val-Tyr
Coenzyme A
Acetyl CoA
Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr (peptide T)
bradykinin fragment 1-8
Tyr-tyr-tyr-tyr-tyr-tyr
Column(s):
Scherzo SM-C18 (150 x 2.0mm)

Exploring different C18 stationary phases for metabolites profiling

Application #:
TI0649
Type:
Application Note
Categories:
Biochemistry/Metabolism
Compounds:
Quinic acid
Malic acid
Tartaric acid
Succinic acid
citric acid
gallic acid
lactic acid
protocatechuic acid
4HPAC
chlorogenic acid
syringic acid
gentisic acid
Column(s):
Scherzo SM-C18 (150 x 2.0mm)

Simulatneous HPLC/LT-ELSD Analysis of Organic and Phenolic Acids

Application #:
TI0648
Type:
Application Note
Categories:
Biochemistry/Metabolism
Vitamins
Compounds:
B1:thiamine
B8:myo-Inositol
B6:Pyridoxine
C:Ascorbic acid
B5:Panthothenic acid
B9: Folic acid
B12: Cyanocobalamin
B2:Riboflavin
B7: Biotin
A:Retinol
K2:Menaquinone
D2:Ergocalciferol
D3:Cholecalciferol
E:a-Tocopherol
K1: Phylloquinone
Column(s):
Scherzo SM-C18 (150 x 2.0mm)

Simulatneous HPLC/LT-ELSD Analysis of Water Soluble and Fat Soluble Vitamins

Application #:
TI0645
Type:
Application Note
Categories:
LC-MS
Botanicals
Compounds:
Amanitin
Phalloidin
Cochicine
Scopolamine
Mesaconitine
Aconitine
Jesaconitine
Solanine
Chaconine
Hypaconitine
Atropine
Column(s):
Scherzo SM-C18 (150 x 2.0mm)

LC-MS/MS Application: Simultaneous determination of phytotoxins in urine

Application #:
TI0642
Type:
Application Note
Categories:
Biochemistry/Metabolism
Compounds:
vanillylmandelic acid
mandelic acid
homovanillic acid
dopamine
Column(s):
Scherzo SM-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)

Scherzo is able to separate mandelic acid and dopamine, which coelute on a conventional C18 column (Unison UK-C18). This is possible because the ionic ligands recognize the small structural differences between the two compounds.

Application #:
TI0641
Type:
Application Note
Categories:
Biochemistry/Metabolism
Compounds:
vanillylmandelic acid
mandelic acid
homovanillic acid
dopamine
Column(s):
Scherzo SM-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)

Catecholamine metabolites

Application #:
TI0640
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Compounds:
dl-chlorpheniramine
dextromethorphan
propylparaben
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Cold medicine compounds

Application #:
TI0628
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
esculin
esculetin
hydroxycoumarin
scopoletin
coumarin
dihydrocoumarin
warfarin
Column(s):
Scherzo SM-C18 (150 x 4.6mm)

Coumarins

Application #:
TI0617
Type:
Application Note
Categories:
Pharmaceuticals and Cosmetics
Compounds:
esculin
esculetin
7-hydroxycoumarin
coumarin
3,4-dihydrocoumarin
warfarin
Column(s):
Scherzo SM-C18 (150 x 4.6mm)
Cadenza CD-C18 (150 x 4.6mm)
Cadenza CW-C18 (150 x 4.6mm)
Cadenza CL-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)
Unison UK-C8 (150 x 4.6mm)
Unison UK-Phenyl (150 x 4.6mm)

Coumarins

Application #:
TI0609
Type:
Application Note
Categories:
Industrial Chemical
Pharmaceuticals & Cosmetics
Compounds:
chromium
copper
zinc
magnesium
calcium
potassium
sodium
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

Cations

Application #:
TI0600
Type:
Application Note
Categories:
Vitamins
LC-MS
Compounds:
thiamine
pyridoxine
nicotinic acid
nicotinamide
pantothenic acid
cyanocobalamin
riboflavin
botin
folic acid
Column(s):
Scherzo SM-C18 (150 x 2.0mm)

Analysis of Water Soluble Vitamins using LCMS-2020

Application #:
TI0599
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
NAD
NADP
NADH
NADPH
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Coenzymes (Nicotinamide adenine dinucleotides)

Application #:
TI0598
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
NAD
NADP
NADH
NADPH
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

Coenzymes (Nicotinamide adenine dinucleotides)

Application #:
TI0592
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
cetirizine
Column(s):
Scherzo SM-C18 (150 x 4.6mm)
Cadenza CD-C18 (150 x 4.6mm)
Cadenza CW-C18 (150 x 4.6mm)
Cadenza CL-C18 (150 x 4.6mm)
Cadenza HS-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)
Unison UK-C8 (150 x 4.6mm)
Unison UK-Phenyl (150 x 4.6mm)

Cetirizine (Antihistamine)

Application #:
TI0588
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
adenosine 5'- monophosphate disodium (AMP) guanosine 5'- monophosphate disodium (GMP)
adenosine 3'
5'-cyclic monophosphate sodium (cAMP)
guanosine 3'
5'-cyclic monophosphate sodium (cGMP)
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Cyclic mononucleotides (cAMP, cGMP)

Application #:
TI0581
Type:
Application Note
Categories:
Industrial Chemical
Environmental and Agricultural
Compounds:
Bisphenol A
Column(s):
Scherzo SM-C18 (75 x 4.6mm)
Cadenza CD-C18 (75 x 4.6mm)
Cadenza CW-C18 (75 x 4.6mm)
Cadenza CL-C18 (75 x 4.6mm)
Cadenza HS-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)
Unison UK-C8 (75 x 4.6mm)
Unison UK-Phenyl (75 x 4.6mm)

Bisphenol A

Application #:
TI0556
Type:
Application Note
Categories:
Environmental and Agricultural
Compounds:
glyphosate
surfactant
Column(s):
Scherzo SM-C18 (250 x 3.0mm)

Herbicide formulation (glyphosate)

Application #:
TI0555
Type:
Application Note
Categories:
Environmental and Agricultural
Compounds:
glufosinate
fosetyl
glyphosate
paraquat dichloride
diquat dibromide
Column(s):
Scherzo SM-C18 (250 x 3.0mm)

Organophosphorous pesticides, quaternary ammonium herbicides

Application #:
TI0552
Type:
Application Note
Categories:
Environmental and Agricultural
Compounds:
sodium arsenite
dimethylarsinic acid (DMAA)
methylarsonic acid (MAA)
disodium hydrogenarsenate heptahydrate
Column(s):
Scherzo SM-C18 (250 x 3.0mm)
Unison UK-C18 (250 x 3.0mm)

Arsenic compounds

Application #:
TI0551
Type:
Application Note
Categories:
Industrial Chemical
Compounds:
Chromium (III) nitrate and ammonium chromate(VI)
Column(s):
Scherzo SM-C18 (50 x 3.0mm)

Chromium (III) nitrate and ammonium chromate(VI)

Application #:
TI0549
Type:
Application Note
Categories:
Industrial Chemical
Environmental and Agricultural
Compounds:
sodium thiosulfate
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

Sodium thiosulfate

Application #:
TI0548
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
succinic acid
malic acid
fumaric acid
malonic acid
citric acid
tartaric acid
maleic acid
Column(s):
Scherzo SM-C18 (250 x 3.0mm)
Unison UK-C18 (250 x 3.0mm)

Organic acids (2)

Application #:
TI0546
Type:
Application Note
Categories:
Industrial Chemical
Compounds:
p-hydroxybenzoic acid
m-hydroxybenzoic acid
terephthalic acid
isophthalic acid
homophthalic acid
o-phthalic acid
hydroxybenzoic acid
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Aromatic carboxylic acids

Application #:
TI0544
Type:
Application Note
Categories:
Industrial Chemical
Pharmaceuticals & Cosmetics
Compounds:
Benzathonium chloride
Column(s):
Scherzo SM-C18 (250 x 3.0mm)
Unison UK-C18 (250 x 3.0mm)

Benzathonium chloride

Application #:
TI0543
Type:
Application Note
Categories:
Industrial Chemical
Pharmaceuticals & Cosmetics
Compounds:
benzalkonium chloride
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Benzalkonium chloride

Application #:
TI0541
Type:
Application Note
Categories:
Industrial Chemical
Food chemistry
Compounds:
Sodium sulfite
Column(s):
Scherzo SM-C18 (250 x 3.0mm)

Sodium Sulfite in Red Wine

Application #:
TI0540
Type:
Application Note
Categories:
Environmental and Agricultural
Compounds:
glyphosate
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

Glyphosate

Application #:
TI0539
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
adenine
guanine
hypoxanthine
xanthine
Column(s):
Scherzo SM-C18 (250 x 4.6mm)
Unison UK-C18 (250 x 4.6mm)

Purine bases

Application #:
TI0537
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
streptomycin sulfate
amikacin disulfate
kanamycin sulfate
tobramycin sulfate
gentamicin sulfate
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

Aminoglycoside antibiotics

Application #:
TI0535
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Botanicals
Saccharides
Compounds:
nojirimycin bisulfite
1-deoxynojirimycin hydrochloride
1-deoxymannojirimycin hydrochloride
Column(s):
Scherzo SM-C18 (250 x 4.6mm)

Nojirimycin relative compounds

Application #:
TI0534
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
hydroxyzine
pamoic acid
Column(s):
Scherzo SM-C18 (50 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)

Hydroxyzine pamoate

Application #:
TI0533
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
fumaric acid
clemastine
Column(s):
Scherzo SM-C18 (50 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)

Clemastine fumarate

Application #:
TI0532
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
tipepidine
hibenzic acid
Column(s):
Scherzo SM-C18 (50 x 3.0mm)

Tipepidine hibenzate

Application #:
TI0531
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
maleic acid
dl-chlorpheniramine
Column(s):
Scherzo SM-C18 (50 x 3.0mm)

Chlorpheniramine maleate

Application #:
TI0530
Type:
Application Note
Categories:
Biochemistry / Metabolism
Industrial Chemical
Compounds:
methyl lactate
lactic acid
levulinic acid
methyl levulinate
Column(s):
Scherzo SM-C18 (150 x 4.6mm)
Unison UK-C18 (150 x 4.6mm)

Levulinic Acid, Lactic Acid and methyl Esters

Application #:
TI0529
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
ADP
AMP
ATP
Column(s):
Scherzo SM-C18 (30 x 3.0mm)
Unison UK-C18 (30 x 3.0mm)

Adenosine Phosphates

Application #:
TI0528
Type:
Application Note
Categories:
Amino acids and peptides
Compounds:
Phe
Leu
Ile
Trp
Met
Val
Pro
Tyr
Thr
Ala
Arg
Ser
Lys
His
Gly
Asn
gln
Cys
Glu
Asp
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

Amino acids: normal phase

Application #:
TI0527
Type:
Application Note
Categories:
Amino acids and peptides
Compounds:
acidic amino acids
hydrophilic amino acids
aliphatic amino acids
branched-chain amino acids
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

Amino acids: acidic condition

Application #:
TI0526
Type:
Application Note
Categories:
Amino acids and peptides
Compounds:
basic amino acids
hydrophilic amino acids
aliphatic amino acids
branched-chain amino acids
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

Amino acids: neutral pH condition

Application #:
TI0525
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Compounds:
doxepine
desipramine
imipramine
nortriptyline
amitriptyline
trimipramine
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

Basic compounds: Antidepressant drugs

Application #:
TI0524
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
L-carnosine
L-anserine nitrate
Inosine 5' monophosphate dipotassium
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Anserine and Related Compounds

Application #:
TI0523
Type:
Application Note
Categories:
Environmental and Agricultural
Compounds:
acetic acid
trifluoroacetic acid
trichloroacetic acid
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Acetic Acid and Trihaloacetic Acids

Application #:
TI0522
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
CMP
UMP
dCMP
dUMP
IMP
GMP
dTMP
AMP
dGMP
dAMP
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Mononucleotides

Application #:
TI0521
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
glutathione reduced (GSH)
glutathione oxidized (GSSG)
Column(s):
Scherzo SM-C18 (50 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)

Glutathiones

Application #:
TI0520
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Biochemistry / Metabolism
Compounds:
sodium chloride
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

Sodium Chloride

Application #:
TI0519
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
DL-mevalonolactone
DL-mevalonic acid
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Mevalonolactone and Mevalonic Acid

Application #:
TI0518
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
sodium gluconate
glyoxylic acid
lactic acid
malic acid
succinic acid
malonic acid
citric acid
fumaric acid
maleic acid
Column(s):
Scherzo SM-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)

Organic Acids

Application #:
TI0517
Type:
Application Note
Categories:
Biochemistry / Metabolism
Compounds:
beta-estradiol 17-(beta-glucuronide)
17beta-estradiol
beta-estradiol 3
17 disulfate
Column(s):
Scherzo SM-C18 (50 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)

Estradiol and Metabolites

Application #:
TI0502
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Column Performance
Compounds:
phenyltrimethylammnonium
benzenesulfonic acid
benzamide
Column(s):
Scherzo SM-C18 (150 x 3.0mm)

The Scherzo SM-C18 column shows excellent batch to batch reproducibility for anionic, cationic, and neutral compounds.

Application #:
TI0501
Type:
Application Note
Categories:
Column performance
Compounds:
acetaminophen
1-hydroxy-7-azabenzotriazole
prednisolone
methyl 3-amino-2-thiophenecarboxylate
6-alpha-methylprednisolone
corticosterone
4-aminobenzophenone
propylparaben
Column(s):
Scherzo SM-C18 (75 x 4.6mm)
Unison UK-C18 (75 x 4.6mm)

Comparison of elution characteristics between Scherzo SM-C18 and Unison UK-C18

Application #:
TI0500
Type:
Application Note
Categories:
Pharmaceuticals & Cosmetics
Steroids
Column Performance
Compounds:
acetaminophen
1-hydroxyN 7-azabenzotriazole
prednisolone
methyl 3-aminoS 2-thiophenecarboxylate
6-alphamethylprednisolone
corticosterone
4-aminobenzophenone
propylparaben
Column(s):
Scherzo SM-C18 (75 x 4.6mm)

The Scherzo SM-C18 column shows excellent batch to batch reproducibility for these small polar molecules.

Application #:
SP0043
Type:
Poster
Categories:
Biochemistry/Metabolism
LC-MS
Compounds:
arginine
ornithine
putrescine
spermine
spermidine
Column(s):
Scherzo SM-C18 (100 x 2.0mm)

Quantitative LC-MS/MS analysis of polyamines and their metabolic precursors in lung tissue

Application #:
SP0042
Type:
Poster
Categories:
Column Performance
Biochemistry/Metabolism
Vitamins
LC-MS
Amino Acids and Peptides
Compounds:
17 alpha-hydroxyprogesterone
glucosamine-6-phosphate
cytosine
octopamine
GABA
hypotaurine
glycine
kynurenine
methionine
arginosuccinic acid
cysteine sulfinic acid
AMP
adenosine
thiamine
ornithine
arginine
alanine
aspartic acid
myo-inositol
glutamic acid
histidine
5-HIAA
lyso-sulfatide
cytidine
isoleucine
1-methylhistidine
3-methylhistidine
S-adenosylhomocystein
glutamine
tyrosine
glycylglycine
valine
cortisone
cAMP
biopterin
tryptophan
3-hydroxybenzoate
orotic acid
nicotinic acid
Phe-Ala,leucine
glycocholic acid
cholic acid
adenine
DOPA
butyric acid
linolenic acid
indole
p-cresol
Column(s):
Scherzo SW-C18 (100 x 2.0mm)
Scherzo SM-C18 (100 x 2.0mm)
Scherzo SS-C18 (100 x 2.0mm)

A Systematic Approach to Development of Analytical Scale and Microflow-based LC-MS Metabolomics Methods to Support Drug Discovery and Development

Application #:
SP0040
Type:
Poster
Categories:
Column Performance
Compounds:
Column(s):
Intrada Amino Acid (0 x 0.0mm)
Intrada WP-RP (0 x 0.0mm)
Scherzo SW-C18 (0 x 0.0mm)
Scherzo SM-C18 (0 x 0.0mm)
Scherzo SS-C18 (0 x 0.0mm)
Cadenza CD-C18 (0 x 0.0mm)
Cadenza CW-C18 (0 x 0.0mm)
Cadenza CL-C18 (0 x 0.0mm)
Cadenza HS-C18 (0 x 0.0mm)
Unison UK-C18 (0 x 0.0mm)
Unison UK-C8 (0 x 0.0mm)
Unison UK-Phenyl (0 x 0.0mm)
Unison UK-Silica (0 x 0.0mm)
Unison UK-Amino (0 x 0.0mm)
Presto FF-C18 (0 x 0.0mm)
Intrada SEC (0 x 0.0mm)
Dacapo DX-C18 (0 x 0.0mm)
Cadenza CX-C18 (0 x 0.0mm)

Imtakt Product Comparisons: Product Descriptions

Application #:
SP0020
Type:
Poster
Categories:
0
Compounds:
0
Column(s):
Scherzo SM-C18 (100 x 2.0mm)

A Novel Separation for Ethyl Glucuronide and Ethyl Sulfate using a Multi - Mode Reversed - Phase Column

Application #:
SP0018
Type:
Poster
Categories:
0
Compounds:
0
Column(s):
Scherzo SM-C18 (150 x 2.0mm)

A high throughput solid phase extraction method for vitamin B3 and related metabolites from pooled human serum using ISOLUTE SCX-3 96 well plates prior to mixed mode LC-MS/MS

Application #:
SP0017
Type:
Poster
Categories:
0
Compounds:
0
Column(s):
Scherzo SM-C18 (50 x 4.6mm)

Mixed Mode Mechanisms in LC: Curse or Cure?

Application #:
SP0005
Type:
Poster
Categories:
0
Compounds:
0
Column(s):
Scherzo SM-C18 (250 x 3.0mm)

Development of simultaneous analysis method on organophosphorous pesticides and quaternary ammonium herbicides using LC/MS

Application #:
SP0004
Type:
Poster
Categories:
0
Compounds:
0
Column(s):
Scherzo SM-C18 (30 x 3.0mm)
Scherzo SM-C18 (50 x 3.0mm)
Scherzo SM-C18 (75 x 4.6mm)
Scherzo SM-C18 (150 x 3.0mm)
Scherzo SM-C18 (150 x 4.6mm)
Scherzo SM-C18 (250 x 3.0mm)
Unison UK-C18 (30 x 3.0mm)
Unison UK-C18 (50 x 3.0mm)
Unison UK-C18 (150 x 3.0mm)
Unison UK-C18 (150 x 4.6mm)

A development and application study for anion exchange + cation exchange + normal phase + reversed-phase multi-mode ODS column

Application #:
JA0019
Type:
Paper
Categories:
0
Compounds:
0
Column(s):
Scherzo SW-C18 (150 x 4.6mm)
Scherzo SM-C18 (150 x 4.6mm)
Scherzo SS-C18 (150 x 4.6mm)

Factors influencing the separation of oligonucleotides using reversed-phase/ion-exchange mixed-mode high performance liquid chromatography columns

Application #:
JA0018
Type:
Paper
Categories:
0
Compounds:
0
Column(s):
Scherzo SM-C18 (150 x 2.0mm)

Global proteomics and metabolomics in cancer biomarker discovery

Application #:
JA0008
Type:
Paper
Categories:
0
Compounds:
0
Column(s):
Scherzo SM-C18 (0 x 0mm)

Sequential elution liquid chromatography can significantly increase the probability of a successful separation by simultaneously increasing the peak capacity and reducing the separation disorder

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