Imtakt has great stationary phase choices for a number of key categories.
Select an option from the list on the left to see the top three most popular columns for that category.
Top 3 Columns for...
LC-MS
With technological innovations like polymeric end-capping and phase stabilization, Imtakt columns are excellent choices for LC-MS work due to low bleed and high efficiency.
- Our first column featuring Dual-Matrix Technology
- Most complete surface coverage of any high pH column on the market
- 2.5µm particle provides superior efficiency
- Extreme polymer surface treatment provides a wide pH range from 1-12
- UHPLC-compatible
- Ideal for basic compounds
- LC-MS analysis of Amino Acids without derivatization
- Full chromatographic resolution of isobaric compounds like LEU and ILE
- Optimized stationary phase for the separation of amino acids and other amine-containing compounds
- Normal phase ligand + Ion exchange
- Can separate 55 amino acids in ten minutes
- High throughput Amino Acid analysis in under 1 minute
- Silica-based SEC Column
- High mechanical strength provides better resolution and longer life
- Compatible with volatile salts
- SEC-MS
- GPC or GFC on one column
Top 3 Columns for...
Pharmaceuticals and Cosmetics
Imtakt columns are uniquely suited for the Pharmaceutical and Cosmetic industries where high throughput and retention of both polar and non-polar small molecules are vital.
- Our first column featuring Dual-Matrix Technology
- Most complete surface coverage of any high pH column on the market
- 2.5µm particle provides superior efficiency
- Extreme polymer surface treatment provides a wide pH range from 1-12
- UHPLC-compatible
- Ideal for basic compounds
- Polar and non-polar retention in Reverse Phase conditions
- Multi-level retention without ion-pairing reagents
- Compatible with LC-MS
- Most unique selectivity of any HPLC column on the market today
- Wide range of method development possibilities
- Can simultaneous run organic, buffer and pH gradients
- Anion Exchange + Cation Exchange + Reverse Phase + Normal Phase
- World’s first reproducible direct injection column
- High efficiency 3µ ODS column with low back-pressure
- Proprietary phase designed to elute compounds larger than 30kDa while retaining small molecules
- Ideal for use with biological samples like blood, urine, plasma, serum or cell culture extracts
- No need for complicated sample preparation, just dilute and shoot
Top 3 Columns for...
Amino Acids and Peptides
We have some very good solutions for analysts working with amino acids and peptides. Our Intrada Amino Acid column is able to separate amino acids without the need for derivatization and our multi-mode Scherzo columns provide a wide range of retention profiles ideally suited for peptide separations. We also have a unique non-porous column called Presto FF-C18 which provides excellent efficiencies for peptide profiling studies.
- LC-MS analysis of Amino Acids without derivatization
- Full chromatographic resolution of isobaric compounds like LEU and ILE
- Optimized stationary phase for the separation of amino acids and other amine-containing compounds
- Normal phase ligand + Ion exchange
- Can separate 55 amino acids in ten minutes
- High throughput Amino Acid analysis in under 1 minute
- Our first column featuring Dual-Matrix Technology
- Most complete surface coverage of any high pH column on the market
- 2.5µm particle provides superior efficiency
- Extreme polymer surface treatment provides a wide pH range from 1-12
- UHPLC-compatible
- Ideal for basic compounds
- Unique ligand density provides excellent stereo selectivity
- High efficiency 3µ ODS column in a 300Å wide pore format
- Excellent for phospholipids and sphingolipids
- Large pore size enables separation of both small and large molecular weight compounds
- Excellent end-capping coverage ideal for highly basic compounds
Top 3 Columns for...
Proteins
We have several solutions for the separation of intact and partially digested proteins. We have two wide pore (300Å) columns with either a C4-like bonded phase or C18. We also have a non-porous C18 column that has incredibly high efficiency and shows excellent separation of molecules up to 50MDa.
- The only 2µ Non-Porous ODS column on the market
- Very high efficiency column
- No band broadening due to reduced mass transfer effect
- Monodispersed particle bed reduces eddy diffusion effect
- Can analyze a wide range of compounds from peptides to large polymers
- 20 kDa to 30 MDa
- Ideal column for protein and large polymer separations
- Silica-based SEC Column
- High mechanical strength provides better resolution and longer life
- Compatible with volatile salts
- SEC-MS
- GPC or GFC on one column
- Optimized stationary phase for the separation of proteins (<300 kDa)
- Wide pore (300Å) reverse phase column designed specifically for protein analysis
- Polymeric end-capping and high efficiency 3µ particle size are ideal for polymers and proteins
- Unique packing reduces carryover
- Improved protein recovery for polymeric separation
- Highly hydrophobic polymer elution made possible by optimal surface polarity
Top 3 Columns for...
Biochemistry/Metabolism
In the fields of biochemistry and metabolism analysts routinely examine mixtures of polar and non-polar analytes. Whether you are looking for metabolic changes in the Kreb’s cycle or citric acid cycle, Imtakt has the range of unique column selectivity to analyze your compounds.
- Polar and non-polar retention in Reverse Phase conditions
- Multi-level retention without ion-pairing reagents
- Compatible with LC-MS
- Most unique selectivity of any HPLC column on the market today
- Wide range of method development possibilities
- Can simultaneous run organic, buffer and pH gradients
- Anion Exchange + Cation Exchange + Reverse Phase + Normal Phase
- LC-MS analysis of Amino Acids without derivatization
- Full chromatographic resolution of isobaric compounds like LEU and ILE
- Optimized stationary phase for the separation of amino acids and other amine-containing compounds
- Normal phase ligand + Ion exchange
- Can separate 55 amino acids in ten minutes
- High throughput Amino Acid analysis in under 1 minute
- World’s first reproducible direct injection column
- High efficiency 3µ ODS column with low back-pressure
- Proprietary phase designed to elute compounds larger than 30kDa while retaining small molecules
- Ideal for use with biological samples like blood, urine, plasma, serum or cell culture extracts
- No need for complicated sample preparation, just dilute and shoot
Top 3 Columns for...
DNA Related Compounds
From large molecular weight intact DNA, to Nucleosides and Nucleotides, Imtakt can provide the best selectivity for your DNA-related analysis needs.
- Polar and non-polar retention in Reverse Phase conditions
- Multi-level retention without ion-pairing reagents
- Compatible with LC-MS
- Most unique selectivity of any HPLC column on the market today
- Wide range of method development possibilities
- Can simultaneous run organic, buffer and pH gradients
- Anion Exchange + Cation Exchange + Reverse Phase + Normal Phase
- High efficiency 3µ columns with mono-dispersed packing for low backpressure
- Normal phase aminopropyl material ideal for analysis of sugars and carbohydrates
- World class reproducibility
- HT and UP hardware able to operate in pressures up to 1000 bar
- High efficiency and available short column dimensions are ideal for high throughput applications
- Unique ligand binding strategy provides dramatically longer lifetimes and lower bleed compared to other amino columns
- The only 2µ Non-Porous ODS column on the market
- Very high efficiency column
- No band broadening due to reduced mass transfer effect
- Monodispersed particle bed reduces eddy diffusion effect
- Can analyze a wide range of compounds from peptides to large polymers
- 20 kDa to 30 MDa
- Ideal column for protein and large polymer separations
Top 3 Columns for...
Vitamins
Vitamin separations can be tricky for a variety of reasons. If you are looking to separate closely related vitamins like 25 Hydroxy Vitamin D isomers then Cadenza CD-C18 with its excellent stereo selectivity might be a good choice. If you are looking to simultaneously separate water and fat-soluble vitamins, then Scherzo SM-C18 multi-mode column might be the right choice. No matter your needs in vitamin separation, Imtakt has the unique selectivities for the best separation.
- Polar and non-polar retention in Reverse Phase conditions
- Multi-level retention without ion-pairing reagents
- Compatible with LC-MS
- Most unique selectivity of any HPLC column on the market today
- Wide range of method development possibilities
- Can simultaneous run organic, buffer and pH gradients
- Anion Exchange + Cation Exchange + Reverse Phase + Normal Phase
- Unique ligand density provides excellent stereo selectivity
- High efficiency 3µ ODS column with low back-pressure
- Excellent for impurity testing or isomer separation
- Selectivity ideal for small molecule pharmaceutical testing or drugs of abuse
- HT and UP hardware able to operate in pressures up to 1000 bar
- High efficiency 3µ columns with mono-dispersed packing for low backpressure
- Normal phase aminopropyl material ideal for analysis of sugars and carbohydrates
- World class reproducibility
- HT and UP hardware able to operate in pressures up to 1000 bar
- High efficiency and available short column dimensions are ideal for high throughput applications
- Unique ligand binding strategy provides dramatically longer lifetimes and lower bleed compared to other amino columns
Top 3 Columns for...
Steroids
Imtakt has some excellent choices for steroid analysis. Our Scherzo multi-mode columns provide both polar and non-polar retention in reverse phase conditions. Our UK-Phenyl columns can provide a high level of selectivity for o,p and m isomers due to pi-pi interactions. Also, our Cadenza CD-C18 column have fantastic steric selectivity for difficult isomer separation.
- Unique ligand density provides excellent stereo selectivity
- High efficiency 3µ ODS column with low back-pressure
- Excellent for impurity testing or isomer separation
- Selectivity ideal for small molecule pharmaceutical testing or drugs of abuse
- HT and UP hardware able to operate in pressures up to 1000 bar
- Polar and non-polar retention in Reverse Phase conditions
- Multi-level retention without ion-pairing reagents
- Compatible with LC-MS
- Most unique selectivity of any HPLC column on the market today
- Wide range of method development possibilities
- Can simultaneous run organic, buffer and pH gradients
- Anion Exchange + Cation Exchange + Reverse Phase + Normal Phase
- High efficiency 3µ columns with mono-dispersed packing for low backpressure
- Unique ligand binding provides no phase collapse in 100% aqueous conditions
- Tri-functional polymeric end-capping reduces unwanted secondary interactions and gives better lifetime
- World class reproducibility
- HT and UP hardware able to operate in pressures up to 1000 bar
- High efficiency and available short column dimensions are ideal for high throughput applications
- Ideal for the separation of o,p and m substituted isomers
Top 3 Columns for...
Food Chemistry
Whether your analyzing food vitamin supplements, amino acid content or sugar profiles, Imtakt has the right column for your food analysis needs.
- LC-MS analysis of Amino Acids without derivatization
- Full chromatographic resolution of isobaric compounds like LEU and ILE
- Optimized stationary phase for the separation of amino acids and other amine-containing compounds
- Normal phase ligand + Ion exchange
- Can separate 55 amino acids in ten minutes
- High throughput Amino Acid analysis in under 1 minute
- Polar and non-polar retention in Reverse Phase conditions
- Multi-level retention without ion-pairing reagents
- Compatible with LC-MS
- Most unique selectivity of any HPLC column on the market today
- Wide range of method development possibilities
- Can simultaneous run organic, buffer and pH gradients
- Anion Exchange + Cation Exchange + Reverse Phase + Normal Phase
- High efficiency 3µ columns with mono-dispersed packing for low backpressure
- Normal phase aminopropyl material ideal for analysis of sugars and carbohydrates
- World class reproducibility
- HT and UP hardware able to operate in pressures up to 1000 bar
- High efficiency and available short column dimensions are ideal for high throughput applications
- Unique ligand binding strategy provides dramatically longer lifetimes and lower bleed compared to other amino columns
Top 3 Columns for...
Industrial Chemical
Industrial chemicals covers a wide range of compounds and analytes. The unique and varied stationary phases available from Imtakt can provide a solution for all of your separation needs.
- Our first column featuring Dual-Matrix Technology
- Most complete surface coverage of any high pH column on the market
- 2.5µm particle provides superior efficiency
- Extreme polymer surface treatment provides a wide pH range from 1-12
- UHPLC-compatible
- Ideal for basic compounds
- Silica-based SEC Column
- High mechanical strength provides better resolution and longer life
- Compatible with volatile salts
- SEC-MS
- GPC or GFC on one column
- Polar and non-polar retention in Reverse Phase conditions
- Multi-level retention without ion-pairing reagents
- Compatible with LC-MS
- Most unique selectivity of any HPLC column on the market today
- Wide range of method development possibilities
- Can simultaneous run organic, buffer and pH gradients
- Anion Exchange + Cation Exchange + Reverse Phase + Normal Phase
Top 3 Columns for...
Environmental and Agricultural
There are a wide range of compounds and analytes in the environmental and agricultural industries. From pesticides to fertilizers, the unique and varied stationary phases available from Imtakt can provide a solution for all of your separation needs.
- Our first column featuring Dual-Matrix Technology
- Most complete surface coverage of any high pH column on the market
- 2.5µm particle provides superior efficiency
- Extreme polymer surface treatment provides a wide pH range from 1-12
- UHPLC-compatible
- Ideal for basic compounds
- Unique ligand density provides excellent stereo selectivity
- High efficiency 3µ ODS column with low back-pressure
- Excellent for impurity testing or isomer separation
- Selectivity ideal for small molecule pharmaceutical testing or drugs of abuse
- HT and UP hardware able to operate in pressures up to 1000 bar
- Polar and non-polar retention in Reverse Phase conditions
- Multi-level retention without ion-pairing reagents
- Compatible with LC-MS
- Most unique selectivity of any HPLC column on the market today
- Wide range of method development possibilities
- Can simultaneous run organic, buffer and pH gradients
- Anion Exchange + Cation Exchange + Reverse Phase + Normal Phase
Top 3 Columns for...
Botanicals
There are a wide range of compounds and analytes in the botanicals industry. From flavanoids to phytohormones, the unique and varied stationary phases available from Imtakt can provide a solution for all of your separation needs.
- World’s first reproducible direct injection column
- High efficiency 3µ ODS column with low back-pressure
- Proprietary phase designed to elute compounds larger than 30kDa while retaining small molecules
- Ideal for use with biological samples like blood, urine, plasma, serum or cell culture extracts
- No need for complicated sample preparation, just dilute and shoot
- Polar and non-polar retention in Reverse Phase conditions
- Multi-level retention without ion-pairing reagents
- Compatible with LC-MS
- Most unique selectivity of any HPLC column on the market today
- Wide range of method development possibilities
- Can simultaneous run organic, buffer and pH gradients
- Anion Exchange + Cation Exchange + Reverse Phase + Normal Phase
- LC-MS analysis of Amino Acids without derivatization
- Full chromatographic resolution of isobaric compounds like LEU and ILE
- Optimized stationary phase for the separation of amino acids and other amine-containing compounds
- Normal phase ligand + Ion exchange
- Can separate 55 amino acids in ten minutes
- High throughput Amino Acid analysis in under 1 minute
Top 3 Columns for...
Direct Serum Injection
We have an excellent solution for those working with biological samples who do not want to have to do lengthy sample preparation before injecting their sample. This is not only time-saving but can significantly reduce cost per sample.
- World’s first reproducible direct injection column
- High efficiency 3µ ODS column with low back-pressure
- Proprietary phase designed to elute compounds larger than 30kDa while retaining small molecules
- Ideal for use with biological samples like blood, urine, plasma, serum or sell culture extracts
- No need for complicated sample preparation, just dilute and shoot
- The only 2µ Non-Porous ODS column on the market
- Very high efficiency column
- No band broadening due to reduced mass transfer effect
- Monodispersed particle bed reduces eddy diffusion effect
- Can analyze a wide range of compounds from peptides to large polymers
- 20 kDa to 30 MDa
- Unique ligand density provides excellent stereo selectivity
- High efficiency 3µ ODS column in a 300Å wide pore format
- Excellent for phospholipids and sphingolipids
- Large pore size enables separation of both small and large molecular weight compounds
- Excellent end-capping coverage ideal for highly basic compounds
Top Column for...
Saccharides
Our Unison UK-Amino column is an excellent choice for saccharide analysis with superior lifetime columns.
- High efficiency 3µ columns with mono-dispersed packing for low backpressure
- Normal phase aminopropyl material ideal for analysis of sugars and carbohydrates
- World class reproducibility
- HT and UP hardware able to operate in pressures up to 1000 bar
- High efficiency and available short column dimensions are ideal for high throughput applications
- Unique ligand binding strategy provides dramatically longer lifetimes and lower bleed compared to other amino columns
Top Columns for...
Oligosaccharides
Our Unison UK-Amino column is an excellent choice for oligosaccharide analysis with superior lifetime columns.
- High efficiency 3µ columns with mono-dispersed packing for low backpressure
- Normal phase aminopropyl material ideal for analysis of sugars and carbohydrates
- World class reproducibility
- HT and UP hardware able to operate in pressures up to 1000 bar
- High efficiency and available short column dimensions are ideal for high throughput applications
- Unique ligand binding strategy provides dramatically longer lifetimes and lower bleed compared to other amino columns
- The only 2µ Non-Porous ODS column on the market
- Very high efficiency column
- No band broadening due to reduced mass transfer effect
- Monodispersed particle bed reduces eddy diffusion effect
- Can analyze a wide range of compounds from peptides to large polymers
- 20 kDa to 30 MDa
Top Column for...
Polysaccharides
Large chain polysaccharides present several unique challenges to chromatographers. With our non-porous Presto FF-C18 column we have an excellent solution for the separation of these polymers.
- The only 2µ Non-Porous ODS column on the market
- Very high efficiency column
- No band broadening due to reduced mass transfer effect
- Monodispersed particle bed reduces eddy diffusion effect
- Can analyze a wide range of compounds from peptides to large polymers
- 20 kDa to 30 MDa
Top 3 Columns for...
Synthetic Polymers
Synthetic polymers present several unique challenges to chromatographers. With our non-porous Presto FF-C18 column and wide pore (300Å) Cadenza CW-C18 we have excellent solution for the separation of these polymers.
- The only 2µ Non-Porous ODS column on the market
- Very high efficiency column
- No band broadening due to reduced mass transfer effect
- Monodispersed particle bed reduces eddy diffusion effect
- Can analyze a wide range of compounds from peptides to large polymers
- 20 kDa to 30 MDa
- Silica-based SEC Column
- High mechanical strength provides better resolution and longer life
- Compatible with volatile salts
- SEC-MS
- GPC or GFC on one column
- Unique ligand density provides excellent stereo selectivity
- High efficiency 3µ ODS column in a 300Å wide pore format
- Excellent for phospholipids and sphingolipids
- Large pore size enables separation of both small and large molecular weight compounds
- Excellent end-capping coverage ideal for highly basic compounds
